Publications

Featured Publications

Bold names denote our lab members
* denotes equal contributions
† denotes co-corresponding authors

• Wang L*†, Wang C*, Moriano JA, Chen S, Zhang S, Mukhtar T, Wang S, Cebrián-Silla A, Bi Q, Augustin JJ, de Oliveira LG, Song M, Ge X, Zuo G, Paredes MF, Huang EJ, Alvarez-Buylla A, Duan X, Li J†, Kriegstein AR†. Molecular and cellular dynamics of the developing human neocortex. Nature. 2025 doi: https://doi.org/ 10.1038/s41586-024-08351-7. [Link]

• Wang L†, Pang K, Zhou L, Cebrián-Silla A, González-Granero S, Wang S, Bi Q, White M, Ho B, Li J, Li T, Perez Y, Huang E, Winkler E, Paredes M, Kovner R, Sestan N, Pollen A, Liu P, Li J, Piao X, García-Verdugo J, Alvarez-Buylla A, Liu Z, Kriegstein AR†. A cross-species proteomic map of synapse development reveals neoteny during human postsynaptic density maturation. Nature. 2023 Oct;622(7981):112-119. [Link]

• Andrews MG*, Siebert C*, Wang L*, White ML, Ross J, Morales R, Donnay M, Bamfonga G, Mukhtar T, McKinney AA, Gemenes K, Wang S, Bi Q, Crouch EE, Parikshak N, Panagiotakos G, Huang EJ, Bhaduri A, Kriegstein AR. LIF signaling regulates outer radial glial to interneuron fate during human cortical development. Cell Stem Cell. 2023 Aug 29;S1934-5909(23)00292-8. [Link]

• Wang L, Pang K, Han K, Adamski CJ, Wang W, He L, Lai JK, Bondar VV, Duman JG, Richman R, Tolias KF, Barth P, Palzkill T, Liu Z, Holder JL Jr, Zoghbi HY. An autism-linked missense mutation in SHANK3 reveals the modularity of Shank3 function. Mol Psychiatry. 2020 Oct;25(10):2534-2555. [Link]

• Wang L, Adamski CJ, Bondar VV, Craigen E, Collette JR, Pang K, Han K, Jain A, Y Jung S, Liu Z, Sifers RN, Holder JL Jr, Zoghbi HY. A kinome-wide RNAi screen identifies ERK2 as a druggable regulator of Shank3 stability. Mol Psychiatry. 2020 Oct;25(10):2504-2516. [Link]

• Pang K*, Wang L*, Wang W, Zhou J, Cheng C, Han K, Zoghbi HY, Liu Z. Coexpression enrichment analysis at the single-cell level reveals convergent defects in neural progenitor cells and their cell-type transitions in neurodevelopmental disorders. Genome Res. 2020 Jun;30(6):835-848. [Link]